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Lyophilization Technology of Vacuum Freeze Dryer

                       
Update:18-07-2019
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Lyophilization of a Vacuum Freeze Dryer was used to pre […]

Lyophilization of a Vacuum Freeze Dryer was used to prepare tissue samples for structural studies (eg, electron microscopy studies). Freeze drying is also used in chemical analysis to obtain dried samples or to concentrate samples to increase analytical sensitivity. Freeze-drying stabilizes the sample components without changing the chemical composition, making it an ideal analytical aid. Freeze drying can occur naturally. In the natural case, this process is slow and unpredictable. Through the freeze-drying system, people have improved and subdivided many steps to speed up the process.

Bell-type Vacuum Freeze Dry Machine: The freeze-drying chamber and the cold trap are upper and lower structures, and the freeze-drying chamber has no pre-freezing function. This type of lyophilizer requires manual operation when it is transferred to the drying process after the material has been pre-frozen. Most of the experimental Freeze Dry Machine are bell-type, with a simple structure and low cost. Most of the freeze-drying chambers use a transparent plexiglass cover to facilitate the observation of the lyophilization of the material.

In-situ freeze-drying machine vacuum freeze-drying machine: the freeze-drying chamber and the cold trap are two independent chambers, and the shelf in the freeze-drying chamber has a cooling function. After the material is placed in the freeze-drying chamber, the material is pre-frozen and dried. The process does not require manual operation. This type of freeze dryer has a complicated manufacturing process and high manufacturing cost, but the in-situ freeze dryer is the development direction of the freeze dryer, an ideal choice for lyophilization process, especially suitable for medicine, biological products and other special products.

Ordinary shelf type vacuum freeze-drying machine: The material is bulk-packed in the material tray and is suitable for lyophilization of food, Chinese herbal medicine and powder materials.

Vacuum lyophilizer with gland type device: suitable for drying of bottled materials in Xilin. When lyophilized, prepare the materials in the vials as needed, float and cover the caps, freeze-dry them, and operate the gland mechanism after drying. The bottle cap can be pressed to avoid secondary pollution, re-adsorb moisture, and easy to store for a long time.